Paradoxine

What is Paradoxine®?

Paradoxine® is a patented extract of Grains of Paradise (Aframomum melegueta), a spice related to ginger that is native to West Africa. Traditionally used in cooking and herbal practices, Grains of Paradise has gained attention in the supplement industry due to its active compounds, particularly 6-Paradol, 6-Gingerol, and 6-Shogaol. Paradoxine® is a standardised form of this extract, designed to provide a consistent concentration of these bioactive compounds. It is commonly included in thermogenic and metabolic support supplements.

How Paradoxine® Works in the Body

Paradoxine® contains 6-Paradol, a bioactive compound that has been studied for its interactions with brown adipose tissue (BAT). Brown adipose tissue plays a role in thermogenesis, the process of heat production in the body. Unlike white fat, which primarily stores energy, brown fat is more metabolically active and contributes to heat generation. Due to these interactions, Paradoxine® is often included in discussions about metabolism and body temperature regulation.

Where is Paradoxine® Found?

Grains of Paradise is naturally found in the seeds of the Aframomum melegueta plant and is traditionally used as a spice in African and Middle Eastern cuisine. The Paradoxine® extract, however, is specifically processed and standardised for use in supplements. It is commonly found in fat-burning formulas, thermogenic pre-workouts, and metabolism-supporting products. It is typically available in capsule or powdered form, often blended with other thermogenic ingredients.

Potential Effects of Supplementation

As with many herbal extracts, individual experiences with Paradoxine® may vary. Some users report increased warmth or sweating, which aligns with its association with thermogenesis. Others take it in the context of metabolic support or body composition goals. However, personal responses depend on factors such as dosage, frequency of use, and individual metabolic differences. Because it interacts with brown adipose tissue, it is often included in formulations designed for heat production and metabolic activity.

Final Thoughts

Paradoxine® is a standardised extract of Grains of Paradise that has gained popularity in thermogenic supplements. Its active compounds, particularly 6-Paradol, have been linked to discussions around metabolism and body temperature regulation. As with any supplement, responses can differ from person to person, and those considering its use should assess their individual needs and tolerance. Whether included in a thermogenic blend or used on its own, Paradoxine® remains an intriguing ingredient in metabolism-focused formulations.